Home > Market Research > Biotechnology > Global Biochip Markets: Microarrays and Lab-on-a-Chip

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Market Study
Published: September 2007
Pages: 314
Tables: 54
From: GBP 3031.25   Buy Now!
Research from: Business Communications Company Inc.
Sector: Biotechnology

REPORT HIGHLIGHTS
The global market for biochips increased from $1,637.5 million in 2006 to an estimated $2,115.6 million by the end of 2008. It should reach $3,840.7 million in 2013, a compound annual growth rate (CAGR) of 12.7%.
DNA microarrays dominate the market today, expected to be worth $947.3 billion in 2007, followed by lab-on-a-chip (LOAC), expected to be worth $625.8 billion in 2007.
The largest market segment for biochips is in drug discovery and development.

INTRODUCTION
Biology is following a path that is reminiscent of the early electronics industry: a miniaturization and large-scale integration process that will revolutionize life science research, drug discovery and development, medical diagnostics and biotechnology. The ongoing miniaturization and large-scale integration process is encompassed in devices known as biochips, including microarrays and lab-on-a-chip microfluidic devices. Biochips represent a diverse group of nanotechnologies that can be expected to exert a significant impact in life science research, diagnostics and medicine.
DNA microarrays are already an established technology generating substantial revenue derived from gene expression, SNP analysis and gene resequencing. The first DNA microarray has recently been approved by the FDA for in-vitro diagnostic applications, and significant market growth can be expected in this application area. Protein microarrays are gaining prominence in the marketplace, while future, emerging array technologies including tissue/cell and glycomics arrays are increasing in importance. Lab-on-chip devices are also making rapid progress in important pharmaceutical and diagnostics market segments.
BCC previously examined the biochip industry in 2004. Given the rapidly advancing bio- and nano-technologies associated with this business, it is timely to re-examine the biochips business.
SCOPE OF STUDY
This report contains:
Descriptions of various biochips including current and potential applications
The current market status of biochip products, trends and forecasts for growth over the next 5 to 10 years
Technological issues, including the latest advances
A discussion of driving forces in the biochip industry on a global basis, including large-scale integration, research initiatives and drug discovery
An examination of biochip companies and industry alliances.
METHODOLOGY
BCC presents an analysis of each of the key market segments that will be commercially important during the next 5 years: research tools, drug discovery and development, diagnostics, DNA sequencing, biodefense, food safety, and forensics.
Based on our analysis, we evaluate the potential applications of biochips in each of the major market segments, and forecast sales revenues for 2008 through 2013.
For research tools and drug discovery and development, the study presents a forecast from 2008 through 2013 for each of the important products and technologies. For diagnostics, the report forecasts from 2008 through 2013 the demand for microarrays and lab-on-a-chip devices by analysis type. Finally, this study forecasts from 2008 through 2013 the market for LOAC devices by end use segment.

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Table of Contents

INTRODUCTION
STUDY GOALS AND OBJECTIVES
REASONS FOR DOING THE STUDY
CONTRIBUTION OF THE STUDY AND FOR WHOM
SCOPE AND FORMAT
METHODOLOGY
INFORMATION SOURCES
RELATED BCC REPORTS
BCC ONLINE SERVICES
DISCLAIMER
SUMMARY
Summary Table:
GLOBAL VALUE OF BIOCHIP PRODUCTS BY TYPE, THROUGH 2013 ($ MILLIONS)
Summary Figure:
GLOBAL VALUE OF BIOCHIP PRODUCTS BY TYPE, 2006-2013 ($ MILLIONS)
OVERVIEW
INTRODUCTION
Table 1 BIOLOGY DOWNSIZING REVOLUTION
Figure 1 EVOLUTION OF BIOCHIPS
BIOCHIP TYPES
Figure 2 CLASSIFICATION OF BIOCHIPS
Table 2 COMPARISON OF THE TWO MAJOR BIOCHIP TYPES
Table 3 BIOCHIP NOMENCLATURE
BIOCHIP TECHNOLOGIES COVERED IN THIS REPORT
Table 4 SCOPE OF THIS REPORT
MARKET POTENTIAL OF BIOCHIPS
Table 5 GLOBAL VALUE OF BIOCHIP MARKET BY END USE, THROUGH 2013 ($ MILLIONS)
Table 6 GLOBAL VALUE OF BIOCHIP PRODUCTS BY GEOGRAPHY, THROUGH 2013 ($ MILLIONS)
DRIVING FORCES FOR GROWTH IN BIOCHIPS MARKETS
Table 7 BIOCHIP MARKET GROWTH DRIVING FORCES
Table 7 (CONTINUED)
BIOCHIPS: A CONVERGENCE OF DIVERSE TECHNOLOGIES
Table 8 MULTIDISCIPLINARY FIELD OF BIOCHIPS
LIFE CYCLE STATUS OF BIOCHIP PRODUCTS
Table 9 LIFE CYCLE STATUS OF BIOCHIP TYPES
COMMERCIAL STATUS OF BIOCHIPS
MICROARRAYS
LOAC
THE BIOCHIP INDUSTRY
Table 10 BIOCHIP INDUSTRY KEY COMPETITORS
MICROARRAY TECHNOLOGIES
INTRODUCTION
THE NANOSCALE WORLD
Table 11 THE NANOSCALE WORLD
Table 12 MICROARRAY TYPES
Table 13 COMPARISON OF DNA AND PROTEIN MICROARRAY TECHNOLOGIES
The Nanoscale World (Continued)
DNA MICROARRAY TECHNOLOGIES
INTRODUCTION
Table 14 DNA MICROARRAY PLATFORM FEATURES
Introduction (Continued)
Table 15 DNA MICROARRAY PLATFORM COMPARISON FOR MAJOR MANUFACTURERS
Introduction (Continued)
STEPS IN THE DNA MICROARRAY EXPERIMENT
DNA MICROARRAY APPLICATIONS
Table 16 DNA MICROARRAY APPLICATIONS
Gene Expression Profiling
Table 17 PROBES FOR GENE EXPRESSION DNA MICROARRAYS
Gene Expression Profiling (Continued)
Table 18 EXAMPLE APPLICATIONS OF GENE EXPRESSION PROFILING
Figure 3 GENETIC ANALYSIS TECHNOLOGY COMPETITIVE SPACE
Table 19 GENETIC ANALYSIS TECHNOLOGIES COMPARISON
Figure 4 COMPETITIVE SPACE FOR GENE
Table 20 PLATFORMS FOR HIGH THROUGHPUT QUANTITATIVE GENE EXPRESSION ANALYSIS
Table 21 GENE EXPRESSION PLATFORMS OF TWO LEADING DNA ARRAY MANUFACTURERS
Table 22 PROBE SENSITIVITY AND SPECIFICITY
SNP Analysis
Figure 5 SNP ANALYSIS PLATFORMS
Epigenetic Analysis
Figure 6 EPIGENOMICS WITHIN THE MOLECULAR BIOLOGY PARADIGM
Dna Methylation
Figure 7 EPIGENETIC CHANGES TO DNA AFFECT GENE EXPRESSION
Histones
Figure 8 HISTONE TAIL REGIONS MODIFIED BY HAT AND HDAC
DNA and Histone Analysis Workflow
Figure 9 UPSTREAM AND DOWNSTREAM STEPS IN EPIGENETIC ANALYSIS
DNA Methylation Microarrays
Chip-On-Chip
Figure 10 CHIP-ON-CHIP PROCEDURE
Table 23 CHIP ASSAYS
Table 24 TECHNOLOGIES FOR MAPPING GENOMIC LOCATION OF CHROMATIN PROTEINS AND ENZYMES
Epigenetic Microarrays
Figure 11 MICROARRAY FEATURE DENSITY
Figure 12 MICROARRAY RESOLUTION
Table 25 MICROARRAY GENOME CONTENT
Table 26 PLATFORMS FOR HIGH DENSITY OLIGONUCLEOTIDE EPIGENETICS ARRAYS
Cytogenetic Analysis
Table 27 COMPARISON OF CHROMOSOMAL CHANGE DETECTION TECHNOLOGIES
Cytogenetic Analysis (Continued)
Figure 13 COMPETITIVE SPACE FOR CNV ANALYSIS
Cytogenetic Analysis (Continued)
Table 28 CGH MICROARRAY PROBE PLATFORMS
Table 29 CGH MICROARRAY TRENDS
Cytogenetic Analysis (Continued)
Table 30 FUTURE TECHNOLOGY NEEDS FOR CGH MICROARRAYS
miRNA Analysis
miRNA Analysis (Continued)
Table 31 TECHNICAL CHALLENGES FOR MIRNAS
ARRAYS ON BEADS
Table 32 ARRAYS ON BEADS
CATALOG AND CUSTOM DNA MICROARRAYS
SUPPLY OF REAGENTS AND SAMPLE PREPARATION FOR MICROARRAYS
TOXICOGENOMICS
DNA SEQUENCING
Figure 14 COMPARISON OF SANGER WITH UHTS DNA SEQUENCING TECHNOLOGIES
Table 33 SINGLE MOLECULE SEQUENCING TECHNOLOGY
Table 34 COMPARISON OF SELECTED DNA SEQUENCING PLATFORMS
Figure 15 COMPETITIVE SPACE FOR HIGH THROUGHPUT GENOMIC ANALYSIS
Table 35 BIOCHIP CONTENT IN NHGRI GRANTEES FOR NEXT GENERATION DNA SEQUENCING, 2005
Table 35 (CONTINUED)
Table 36 NEXT GENERATION DNA SEQUENCING COMPANIES
RESEQUENCING APPROACHES IN DIAGNOSTICS
DNA MICROARRAY MANUFACTURING
Figure 16 DNA MICROARRAY MANUFACTURING TECHNOLOGIES
DNA Microarray Manufacturing (Continued)
Table 37 DNA MICROARRAY PROBE DENSITY TRENDS
DNA MICROARRAY TECHNOLOGY TRENDS
DNA MICROARRAY TECHNOLOGY CHALLENGES
Figure 17 DNA MICROARRAY COST-VOLUME CURVE
PROTEIN MICROARRAY TECHNOLOGIES
INTRODUCTION
Figure 18 IMPORTANCE OF PROTEINS
PROTEOMICS WORKFLOW
Figure 19 PROTEIN ANALYSIS APPROACHES CONTRASTED
PROTEIN MICROARRAY DESIGN FEATURES
Table 38 PROTEIN MICROARRAY PLATFORMS
PROTEIN MICROARRAY APPLICATIONS AS RESEARCH TOOLS
Table 39 PROTEIN MICROARRAYS AS RESEARCH TOOLS
Protein Microarray Applications as ? (Continued)
PROTEIN MICROARRAY TYPES
Table 40 PROTEIN MICROARRAY PRODUCT TYPES
Protein Microarray Types (Continued)
Protein Microarray Types (Continued)
PROTEIN MICROARRAY TECHNOLOGY CHALLENGES
Table 41 PROTEIN MICROARRAY TECHNICAL CHALLENGES
Protein Microarray Technology Challenges (Continued)
PROTEIN MICROARRAY TECHNOLOGY TRENDS
Table 42 PROTEIN MICROARRAY TECHNOLOGY TRENDS
EMERGING MICROARRAY TECHNOLOGIES
Table 43 EMERGING MICROARRAY TECHNOLOGIES
GLYCOMICS MICROARRAYS
Glycomics Microarrays (Continued)
TISSUE MICROARRAYS
Tissue Microarrays (Continued)
FUNCTIONAL CELL MICROARRAYS
Table 44 U.S. GOVERNMENT INITIATIVES PROMOTING EMERGING MICROARRAYS
MICROARRAY TECHNOLOGY TRENDS
Table 45 MICROARRAY TECHNOLOGY TRENDS
MICROARRAY TECHNOLOGY TRENDS (CONTINUED)
LAB-ON-A-CHIP TECHNOLOGIES
INTRODUCTION
Table 46 MICROFLUIDICS PRODUCT LIFE CYCLE STAGE
Table 47 LOAC SUBSTRATE TECHNOLOGIES
LAB-ON-A-CHIP TYPES
Table 48 LAB-ON-A-CHIP TYPES
IN-VITRO PROTEOMICS
ELECTROPHORESIS ON A CHIP
STRUCTURAL PROTEOMICS
PCR ON A CHIP
IMMUNOASSAYS ON A CHIP
Immunoassays on a Chip (Continued)
Table 49 IMMUNOASSAY-ON-A-CHIP APPLICATIONS
LAB-ON-A-CHIP MAJOR APPLICATIONS
Table 50 LAB-ON-A-CHIP MARKET SEGMENTS
Table 50 (CONTINUED)
Table 51 MICROFLUIDIC SYSTEMS ADVANTAGES FOR BIOCHEMICAL ANALYSIS
LAB-ON-A-CHIP KEY TECHNOLOGY TRENDS
Table 52 LAB-ON-A-CHIP KEY TECHNOLOGY TRENDS
Table 53 LOAC TECHNOLOGY PLATFORMS
LAB-ON-A-CHIP TECHNOLOGY CHALLENGES
Table 54 LAB-ON-A-CHIP TECHNOLOGY CHALLENGES
LAB-ON-A-CHIP TECHNOLOGY ... (CONTINUED)
LIST OF TABLES
Summary Table:
GLOBAL VALUE OF BIOCHIP PRODUCTS BY TYPE, THROUGH 2013 ($ MILLIONS)
Table 1 BIOLOGY DOWNSIZING REVOLUTION
Table 2 COMPARISON OF THE TWO MAJOR BIOCHIP TYPES
Table 3 BIOCHIP NOMENCLATURE
Table 4 SCOPE OF THIS REPORT
Table 5 GLOBAL VALUE OF BIOCHIP MARKET BY END USE, THROUGH 2013 ($ MILLIONS)
Table 6 GLOBAL VALUE OF BIOCHIP PRODUCTS BY GEOGRAPHY, THROUGH 2013 ($ MILLIONS)
Table 7 BIOCHIP MARKET GROWTH DRIVING FORCES
Table 8 MULTIDISCIPLINARY FIELD OF BIOCHIPS
Table 9 LIFE CYCLE STATUS OF BIOCHIP TYPES
Table 10 BIOCHIP INDUSTRY KEY COMPETITORS
Table 11 THE NANOSCALE WORLD
Table 12 MICROARRAY TYPES
Table 13 COMPARISON OF DNA AND PROTEIN MICROARRAY TECHNOLOGIES
Table 14 DNA MICROARRAY PLATFORM FEATURES
Table 15 DNA MICROARRAY PLATFORM COMPARISON FOR MAJOR MANUFACTURERS
Table 16 DNA MICROARRAY APPLICATIONS
Table 17 PROBES FOR GENE EXPRESSION DNA MICROARRAYS
Table 18 EXAMPLE APPLICATIONS OF GENE EXPRESSION PROFILING
Table 19 GENETIC ANALYSIS TECHNOLOGIES COMPARISON
Table 20 PLATFORMS FOR HIGH THROUGHPUT QUANTITATIVE GENE EXPRESSION ANALYSISTWO LEADING DNA ARRAY MANUFACTURERS
Table 22 PROBE SENSITIVITY AND SPECIFICITY
Table 23 CHIP ASSAYS
Table 24 TECHNOLOGIES FOR MAPPING GENOMIC LOCATION OF CHROMATIN PROTEINS AND ENZYMES
Table 25 MICROARRAY GENOME CONTENT
Table 26 PLATFORMS FOR HIGH DENSITY OLIGONUCLEOTIDE EPIGENETICS ARRAYS
Table 27 COMPARISON OF CHROMOSOMAL CHANGE DETECTION TECHNOLOGIES
Table 28 CGH MICROARRAY PROBE PLATFORMS
Table 29 CGH MICROARRAY TRENDS
Table 30 FUTURE TECHNOLOGY NEEDS FOR CGH MICROARRAYS
Table 31 TECHNICAL CHALLENGES FOR MIRNAS
Table 32 ARRAYS ON BEADS
Table 33 SINGLE MOLECULE SEQUENCING TECHNOLOGY
Table 34 COMPARISON OF SELECTED DNA SEQUENCING PLATFORMS
Table 35 BIOCHIP CONTENT IN NHGRI GRANTEES FOR NEXT GENERATION DNA SEQUENCING,
Table 36 NEXT GENERATION DNA SEQUENCING COMPANIES
Table 37 DNA MICROARRAY PROBE DENSITY TRENDS
Table 38 PROTEIN MICROARRAY PLATFORMS
Table 39 PROTEIN MICROARRAYS AS RESEARCH TOOLS
Table 40 PROTEIN MICROARRAY PRODUCT TYPES
Table 41 PROTEIN MICROARRAY TECHNICAL CHALLENGES
Table 42 PROTEIN MICROARRAY TECHNOLOGY TRENDS
Table 43 EMERGING MICROARRAY TECHNOLOGIES
Table 44 U.S. GOVERNMENT INITIATIVES PROMOTING EMERGING MICROARRAYS
Table 45 MICROARRAY TECHNOLOGY TRENDS
Table 46 MICROFLUIDICS PRODUCT LIFE CYCLE STAGE
Table 47 LOAC SUBSTRATE TECHNOLOGIES
Table 48 LAB-ON-A-CHIP TYPES
Table 49 IMMUNOASSAY-ON-A-CHIP APPLICATIONS
Table 50 LAB-ON-A-CHIP MARKET SEGMENTS
Table 51 MICROFLUIDIC SYSTEMS ADVANTAGES FOR BIOCHEMICAL ANALYSIS
Table 52 LAB-ON-A-CHIP KEY TECHNOLOGY TRENDS
Table 53 LOAC TECHNOLOGY PLATFORMS
Table 54 LAB-ON-A-CHIP TECHNOLOGY CHALLENGES
LIST OF FIGURES
Summary Figure:
GLOBAL VALUE OF BIOCHIP PRODUCTS BY TYPE, 2006-2013 ($ MILLIONS)
Figure 1 EVOLUTION OF BIOCHIPS
Figure 2 CLASSIFICATION OF BIOCHIPS
Figure 3 GENETIC ANALYSIS TECHNOLOGY COMPETITIVE SPACE
Figure 4 COMPETITIVE SPACE FOR GENE
Figure 5 SNP ANALYSIS PLATFORMS
Figure 6 EPIGENOMICS WITHIN THE MOLECULAR BIOLOGY PARADIGM
Figure 7 EPIGENETIC CHANGES TO DNA AFFECT GENE EXPRESSION
Figure 8 HISTONE TAIL REGIONS MODIFIED BY HAT AND HDAC
Figure 9 UPSTREAM AND DOWNSTREAM STEPS IN EPIGENETIC ANALYSIS
Figure 10 CHIP-ON-CHIP PROCEDURE
Figure 11 MICROARRAY FEATURE DENSITY
Figure 12 MICROARRAY RESOLUTION
Figure 13 COMPETITIVE SPACE FOR CNV ANALYSIS
Figure 14 COMPARISON OF SANGER WITH UHTS DNA SEQUENCING TECHNOLOGIES
Figure 15 COMPETITIVE SPACE FOR HIGH THROUGHPUT GENOMIC ANALYSIS
Figure 16 DNA MICROARRAY MANUFACTURING TECHNOLOGIES
Figure 17 DNA MICROARRAY COST-VOLUME CURVE
Figure 18 IMPORTANCE OF PROTEINS
Figure 19 PROTEIN ANALYSIS APPROACHES CONTRASTED

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