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Home > Market Research > Prescription Medicines > The Pharmaceutical Market: France
Espicom’s in-depth pharmaceutical market reports are ideal for executives wanting to understand the key drivers in pharmaceutical markets and have access to a wealth of statistical data. Each report opens with an outlook section that provides analysis of the market, 5-year market forecasts, national data projections, market outlook and key developments such as regulation, pricing/reimbursement, intellectual property, health facilities and government policy. The report also provides extensive background information, population trends, health status, health expenditure, organisation & administration, hospital services, medical personnel, healthcare development, market access information, trade data for raw materials and finished products and essential industry contacts. Included with the report are 3 free quarterly updated outlook reports, enabling you to keep up to date with market developments for a year.
Overall market growth has been comparatively low at around 5.0% per annum and is expected to average 2.7% in local terms in the medium term with government cost-containment programmes exerting downward pressure on reimbursable products. The hospital market has been much more dynamic with growth rates twice this figure in recent years, although growth rates are now falling due to greater regulatory controls in this sector and fewer innovative drugs coming to market.
The underdeveloped generics market is undergoing rapid expansion boosted by government incentives and the loss of patent protection for several high-volume products. The stagnating OTC market has also started to expand as a result of government moves to end reimbursement for a wide range of products assigned a low medical value rating.
France is the third largest producer of pharmaceuticals in the world, accounting for 7% of global pharmaceutical output. Many multinationals have strategic manufacturing sites in France. However, the country is gradually losing out competitively to other European countries with more attractive business environments, such as Ireland, and to low cost producers in Eastern Europe and South America.
The increasingly competitive business environment has resulted in many smaller independent producers being acquired by multinational groups, recent examples being the acquisition of Fournier Pharma by Solvay of Belgium and the acquisition of Negma-Lerads by Wockhardt of India.
France has also lost ground in the field of pharmaceutical research with the majority of multinationals preferring to concentrate their research efforts in their home country or in the US. Oncology research remains one of the few growth areas, due to the launch of a national cancer plan.
Highly detailed report content
MARKET OUTLOOK Key national data projections
Pharmaceutical Market Analysis Current market size Market structure Unique 5-year market projections Imports Domestic manufacturing Exports Research & development
Pharmaceutical regulatory analysis Including regulation, pricing & reimbursement and intellectual property
Pharmaceutical distribution
Healthcare analysis Including demographics, healthcare system, health expenditure, healthcare infrastructure and personnel
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Table of Contents
EXECUTIVE SUMMARY 1 INTRODUCTION . 2 PHARMACEUTICAL MARKET ANALYSIS . 4 Size . 4 Market Structure . 7 Retail Pharmacy Sector 7 Reimbursable Drugs – Retail Pharmacy Market 12 CNAM Spending on Reimbursable Drugs 15 Hospital Sector 20 Generics Sector 22 OTC Sector . 26 Projections & Outlook . 28 Cost Containment Measures for the Health Sector During 2010 . 28 Market Growth of 2% Forecast for 2009 29 Imports 33 Domestic Manufacturing . 37 Domestic Production . 37 Trade Associations 38 LEEM / LEEM Recherche 38 LIR . 38 GEMME . 38 Local Manufacturers 39 Ipsen 39 Pierre Fabre . 39 Sanofi-Aventis . 40 Sanofi Pasteur . 41 Servier . 41 Multinational Manufacturers 42 AstraZeneca 42 Bristol-Myers Squibb . 42 Eli Lilly 43 GSK . 43 MSD . 43 Pfizer 43 Pharmaceutical Industry Expected to Downsize in Coming Years 43 Exports 44 Research & Development . 48 Sanofi-Aventis . 48 Servier . 49 Pierre Fabre . 49 FRANCE PHARMA OUTLOOK Pharma Outlook espicom BUSINESS INTELLIGENCE ii Quarter I 2010 Ipsen 49 LEEM-Recherche 50 PHARMACEUTICAL REGULATORY ANALYSIS . 52 Pharmaceutical Regulation . 52 EU Drug Regulation 52 Centralised Procedure . 52 EMEA . 53 Generic drugs 53 Healthcare Products Safety Agency . 53 Pharmaceutical Registration . 53 Post-marketing surveillance 53 Advertising 54 Pricing & Reimbursement . 54 Pricing . 54 Pricing of reimbursable medicines in the retail pharmacy market 54 Price revisions . 55 Pricing activity 56 State-Industry Framework Agreements 57 Pharmacy margins . 58 Reference pricing (TFR) 58 Pricing of hospital medicines . 58 Reimbursement . 59 Social Security Pharmaceutical Reimbursement Spending Trends . 60 Intellectual Property 60 Supplementary Protection Certificates . 60 Data Exclusivity . 60 PHARMACEUTICAL DISTRIBUTION 61 Wholesaling 61 Distributors 61 Alliance Healthcare 61 CERP . 61 OCP . 61 Phoenix Pharma 62 Retailing 62 HEALTHCARE ANALYSIS 63 Demographics . 63 Population . 63 Birth Rate . 64 Death Rate. 64 Infant Mortality . 64 Maternal Mortality 64 Life Expectancy at Birth . 64 PHARMA OUTLOOK FRANCE Pharma Outlook espicom BUSINESS INTELLIGENCE Quarter I 2010 iii Public Health . 65 Causes of Death 65 Incidence of Communicable Diseases . 66 HIV/AIDS . 66 Hepatitis C / Hepatitis B . 66 Incidence of Non-communicable Diseases 67 Cancer . 68 Cardiovascular Diseases . 69 Diabetes. 69 Hearing Impairment . 70 Mental/ Neurological disorders 70 Musculoskeletal disorders . 71 Renal Disease . 71 Respiratory Disorders 71 Healthcare System 72 National Health Agencies 72 Regional Health Agencies . 72 Public Hospitals . 73 Hospital Restructuring . 73 Regional Health Organisation Plans (SROS) . 73 Ambulatory Services 74 Health Insurance System 75 Health Expenditure . 76 Spending on Pharmaceuticals . 77 Healthcare Infrastructure 78 Public Hospitals . 79 Private Hospital . 79 Non-Profitmaking Hospitals . 79 Commercial Clinics 80 Compagnie Générale de Santé (CGS) . 80 Capio Santé . 80 Médi-Partenaires . 80 Vitalia . 81 Vedici . 81 Regional chains . 81 Inpatient Analysis 81 Surgical Activity . 83 Obstetric Activity . 84 Diagnostic & Therapeutic Activity in the Private Sector . 84 Ambulatory Activity 85 Home Hospitalisation 85 Healthcare Personnel . 86 DIRECTORY 89 FRANCE PHARMA OUTLOOK Pharma Outlook espicom BUSINESS INTELLIGENCE iv Quarter I 2010 Government Organisations . 89 Trade Associations . 89 Methodology & Sources . 90 List of Tables Summary of Key Data Projections, 2010-2015 . 3 Summary of the French Pharmaceutical Market at Retail Prices, 2010 . 4 Sales of Pharmaceuticals for Human Use, 2001-2007 (manufacturers’ prices) 5 Sales of Pharmaceuticals for Human Use, 2001-2007 (Euros Million) . 5 Average Per Capita Consumption of Selected Drug Categories, 2006 6 Top 20 Therapeutic Classes in Retail Pharmacy Drug Market, 2007 9 Top Selling Products’ Share of the Retail Pharmacy Market, 2005-2007 (%) 9 Top 50 Products in Retail Pharmacy Market by Value Ranking, 2007 . 10 Growth in Pharmaceutical Consumption, Reimbursable Products, 2003-2008 12 Reimbursable Pharmaceutical Growth by Principal Factor, 2000-2008 (%) 12 Pharmacy Spending on Reimbursable Products by Reimbursement Status, 2007-2008 . 13 Top Ten Contributors to Increased Spending on Reimbursable Products, 2007 . 13 Top Five Contributors to Reduced Spending on Reimbursable Products, 2008 14 Top Ten Contributors to Reduced Spending on Reimbursable Products, 2007 . 14 CNAM Spending on Reimbursable Drugs, Ambulatory Sector, 2008 15 CNAM Spending Trends on Reimbursable Drugs, by Product Category, 2005-2008 . 15 Pharmaceutical Expenditure Growth by Product Type, 2008 . 18 Top 50 Prescription Products Reimbursed in 2008 . 19 Spending on Specialist Drugs Financed Separately From DRG-Based Fee System, 2006-2008 20 Top 20 Therapeutic Classes in Hospital Drug Market, 2007 . 20 Top 50 Products in Hospital Market by Value Ranking, 2007 . 21 Sales of Reimbursable Generics in Retail Pharmacy Market, 2002-2007 22 Reimbursable Market by Patent Status, 2007 . 22 Top 30 Best selling generics, 2007 23 Generics Penetration Objectives by Volume, 2008 24 Companies Serving the French Generics Market, 2006 25 Market Projections, 2010-2015 . 28 CNAM Spending on Drugs, Ambulatory Sector, January-June 2009 (Euros Million) . 29 Espicom Analysis of the French Pharmaceutical Market, 2010 31 SWOT Analysis of the French Pharmaceutical Market, 2010 32 Pharmaceutical Imports by Category, 2003-2007 (US$ millions) 33 PHARMA OUTLOOK FRANCE Pharma Outlook espicom BUSINESS INTELLIGENCE Quarter I 2010 v Pharmaceutical Import Trends 33 Leading Suppliers of Raw Materials, 2007 (US$000s) . 36 Leading Suppliers of Antisera & Vaccines, 2007 (US$000s) . 36 Leading Suppliers of Medicaments, 2007 (US$000s) 36 Trends in Pharmaceutical Manufacturing Industry, 2000-2006 37 Pharmaceutical Manufacturing Industry by Principal Sector, 2006 . 37 Production of Medicaments and Vaccines for Human Use, 2004-2007 (Euros Million) 37 Members of LEEM Recherche, 2007 38 Members of LIR, 2007 . 38 Members of GEMME, 2007 . 38 Pharmaceutical Exports by Category, 2003-2007 (US$ millions) . 44 Pharmaceutical Export Trends 44 Leading Destinations of Raw Materials, 2007 (US$000s) 47 Leading Destinations of Antisera & Vaccines, 2007 (US$000s) 47 Leading Destinations of Medicaments, 2007 (US$000s) . 47 Pharmaceutical Industry R&D Expenditure, 1995-2006 . 51 Drug Pricing Applications Submitted by Type, 2008 . 56 Average Number of Days Taken to Process First-Time Registrations, 2008 56 Taxes and Other Financial Contributions Imposed on Pharmaceutical Companies, 2000-2007 . 57 Distribution of the Pharmaceutical Market According to Reimbursement Rate, 2007-2008 60 Social Security Drug Reimbursement, 2003-2006 60 Active Pharmacies According to Legal Status, 2001 . 62 Summary of Demographic Data 63 Projected Population, 2010-2015 . 63 Causes of Death, 2006 65 Long-Term Illnesses (New Cases), 2003-2007 67 Projected Growth in Patients with Cancer, Régime Général, 2006-2015 . 68 Projected Growth in Patients with Cardiovascular Disorders, Régime Général, 2006-2015 69 Projected Growth in Patients with Mental/Neurological Disorders, Régime Général, 2006-2015 70 Summary of Healthcare Expenditure 76 Health Expenditure, 2000-2008 76 Projected Health Expenditure, 2010-2015 . 77 Spending Trends on Pharmaceuticals, Ambulatory Sector, 2003-2008 . 77 Pharmaceutical Expenditure by Source of Funding, 2003-2008 (%) 77 Summary of Hospitals & Beds . 78 Selected Medical Equipment Installed at French Hospitals by Sector, 2007 78 Hospital Bed Projections, 2009-2014 78 FRANCE PHARMA OUTLOOK Pharma Outlook espicom BUSINESS INTELLIGENCE vi Quarter I 2010 Hospital Activity, 2004-2007 . 82 Hospital Activity by Specialty, 2007 82 Hospital Activity in Short-Stay Units, 2003-2007 . 82 Diagnostic and Therapeutic Procedures Performed in Public and Private Hospitals, 2006 83 Medical Personnel, 2000-2007 . 86 Doctors by Specialty and Sector, 2003-2007 87 Doctors by Sector, 2007 . 88 Projected Number of Physicians, 2010-2015 88 List of Charts Pharmaceutical Market Growth Rates by Sector, 1997-2007 5 Distribution of the French Pharmaceutical Market by Size of Market Share, 2007 (%) 6 Retail Pharmacy Market by Product Status, 2007, Value % 8 Retail Pharmacy Market by Product Status, 2007, Volume % . 8 Retail Pharmacy Market Growth Rates, 2000-2007 9 Retail Pharmacy Market: Turnover by Therapeutic Area, 2007 (%) 11 Retail Pharmacy Market: Volume by Therapeutic Area, 2007 (%) 11 Distribution of the Reimbursable Market by Age of Presentations, 2008 (%) . 14 Growth in Reimbursable Drug Expenditure, Régime Général, 2002-2009 . 16 Growth in Drug Reimbursements by Category, Régime Général, 2008 (Euros Million) . 17 Growth in Drug Reimbursements by Prescriber, Régime Général, 2008 (Euros Million) . 17 Distribution of the OTC Pharmaceutical Market by Product Status, 2008 (%) 26 Annual Growth Rate in Spending on Reimbursable Drugs, 2000-2009 (%) . 30 Radar Graph of the French Pharmaceutical Market, 2010. 32 Pharmaceutical Imports, 1999-2007 33 Change in Pharmaceutical Imports, 1999-2007 (%) . 34 Pharmaceutical Imports by Category 2007 (%) 34 Leading Suppliers of Pharmaceuticals, 2007 (%) 35 Pharmaceutical Exports, 1999-2007 44 Change in Pharmaceutical Exports, 1999-2007 (%) . 45 Pharmaceutical Exports by Category, 2007 (%) . 45 Leading Destinations of Pharmaceuticals, 2007 46 R&D Employment within the French Pharmaceutical Industry, 1995-2005 (%) . 51 Clinical Trials Initiated, 1995-2006 (%) 51
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